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The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function

Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis (RA), exhibits anti-inflammatory, antiproliferative and immunosuppressive effects. Although most of the beneficial effects of leflunomide have been attributed to its antimetabolite activity, main...

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Detalles Bibliográficos
Autores principales:	Kirsch, Bernhard M, Zeyda, Maximilian, Stuhlmeier, Karl, Grisar, Johannes, Smolen, Josef S, Watschinger, Bruno, Stulnig, Thomas M, Hörl, Walter H, Zlabinger, Gerhard J, Säemann, Marcus D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174963/ https://www.ncbi.nlm.nih.gov/pubmed/15899055 http://dx.doi.org/10.1186/ar1727

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