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The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration
In this study, we investigated the hypotheses that in human intervertebral disc (IVD) degeneration there is local production of the cytokine IL-1, and that this locally produced cytokine can induce the cellular and matrix changes of IVD degeneration. Immunohistochemistry was used to localize five me...
Autores principales: | Le Maitre, Christine Lyn, Freemont, Anthony J, Hoyland, Judith Alison |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175026/ https://www.ncbi.nlm.nih.gov/pubmed/15987475 http://dx.doi.org/10.1186/ar1732 |
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