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Perforin deficiency attenuates collagen-induced arthritis

Collagen-induced arthritis (CIA), an approved animal model for rheumatoid arthritis, is thought to be a T cell-dependent disease. There is evidence that CD8(+ )T cells are a major subset controlling the pathogenesis of CIA. They probably contribute to certain features of disease, namely tissue destr...

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Detalles Bibliográficos
Autores principales:	Bauer, Kristin, Knipper, Annika, Tu-Rapp, Hoang, Koczan, Dirk, Kreutzer, Hans-Jürgen, Nizze, Horst, Mix, Eilhard, Thiesen, Hans-Juergen, Holmdahl, Rikard, Ibrahim, Saleh M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175039/ https://www.ncbi.nlm.nih.gov/pubmed/15987490 http://dx.doi.org/10.1186/ar1758

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