Mutation analysis of the ATR gene in breast and ovarian cancer families

INTRODUCTION: Mutations in BRCA1, BRCA2, ATM, TP53, CHK2 and PTEN account for only 20–30% of the familial aggregation of breast cancer, which suggests the involvement of additional susceptibility genes. The ATR (ataxia-telangiectasia- and Rad3-related) kinase is essential for the maintenance of geno...

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Detalles Bibliográficos
Autores principales: Heikkinen, Katri, Mansikka, Virpi, Karppinen, Sanna-Maria, Rapakko, Katrin, Winqvist, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175065/
https://www.ncbi.nlm.nih.gov/pubmed/15987455
http://dx.doi.org/10.1186/bcr1037

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