Inhibition of O(6)-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli

The alkyltransferase-like (ATL) proteins contain primary sequence motifs resembling those found in DNA repair O(6)-alkylguanine-DNA alkyltransferase proteins. However, in the putative active site of ATL proteins, a tryptophan (W(83)) residue replaces the cysteine at the known active site of alkyltra...

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Detalles Bibliográficos
Autores principales: Pearson, Steven J., Ferguson, Jennifer, Santibanez-Koref, Mauro, Margison, Geoffrey P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175458/
https://www.ncbi.nlm.nih.gov/pubmed/16027108
http://dx.doi.org/10.1093/nar/gki696

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