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Single-feature polymorphism discovery in the barley transcriptome
A probe-level model for analysis of GeneChip gene-expression data is presented which identified more than 10,000 single-feature polymorphisms (SFP) between two barley genotypes. The method has good sensitivity, as 67% of known single-nucleotide polymorphisms (SNP) were called as SFPs. This method is...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175974/ https://www.ncbi.nlm.nih.gov/pubmed/15960806 http://dx.doi.org/10.1186/gb-2005-6-6-r54 |
_version_ | 1782124554183770112 |
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author | Rostoks, Nils Borevitz, Justin O Hedley, Peter E Russell, Joanne Mudie, Sharon Morris, Jenny Cardle, Linda Marshall, David F Waugh, Robbie |
author_facet | Rostoks, Nils Borevitz, Justin O Hedley, Peter E Russell, Joanne Mudie, Sharon Morris, Jenny Cardle, Linda Marshall, David F Waugh, Robbie |
author_sort | Rostoks, Nils |
collection | PubMed |
description | A probe-level model for analysis of GeneChip gene-expression data is presented which identified more than 10,000 single-feature polymorphisms (SFP) between two barley genotypes. The method has good sensitivity, as 67% of known single-nucleotide polymorphisms (SNP) were called as SFPs. This method is applicable to all oligonucleotide microarray data, accounts for SNP effects in gene-expression data and represents an efficient and versatile approach for highly parallel marker identification in large genomes. |
format | Text |
id | pubmed-1175974 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-11759742005-07-17 Single-feature polymorphism discovery in the barley transcriptome Rostoks, Nils Borevitz, Justin O Hedley, Peter E Russell, Joanne Mudie, Sharon Morris, Jenny Cardle, Linda Marshall, David F Waugh, Robbie Genome Biol Method A probe-level model for analysis of GeneChip gene-expression data is presented which identified more than 10,000 single-feature polymorphisms (SFP) between two barley genotypes. The method has good sensitivity, as 67% of known single-nucleotide polymorphisms (SNP) were called as SFPs. This method is applicable to all oligonucleotide microarray data, accounts for SNP effects in gene-expression data and represents an efficient and versatile approach for highly parallel marker identification in large genomes. BioMed Central 2005 2005-05-11 /pmc/articles/PMC1175974/ /pubmed/15960806 http://dx.doi.org/10.1186/gb-2005-6-6-r54 Text en Copyright © 2005 Rostoks et al.; licensee BioMed Central Ltd. |
spellingShingle | Method Rostoks, Nils Borevitz, Justin O Hedley, Peter E Russell, Joanne Mudie, Sharon Morris, Jenny Cardle, Linda Marshall, David F Waugh, Robbie Single-feature polymorphism discovery in the barley transcriptome |
title | Single-feature polymorphism discovery in the barley transcriptome |
title_full | Single-feature polymorphism discovery in the barley transcriptome |
title_fullStr | Single-feature polymorphism discovery in the barley transcriptome |
title_full_unstemmed | Single-feature polymorphism discovery in the barley transcriptome |
title_short | Single-feature polymorphism discovery in the barley transcriptome |
title_sort | single-feature polymorphism discovery in the barley transcriptome |
topic | Method |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175974/ https://www.ncbi.nlm.nih.gov/pubmed/15960806 http://dx.doi.org/10.1186/gb-2005-6-6-r54 |
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