Conservation anchors in the vertebrate genome

Genomic segments that do not code for proteins yet show high conservation among vertebrates have recently been identified by various computational methodologies. We refer to them as ANCORs (ancestral non-coding conserved regions). The frequency of individual ANCORs within the genome, along with thei...

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Detalles Bibliográficos
Autores principales: Aloni, Ronny, Lancet, Doron
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175977/
https://www.ncbi.nlm.nih.gov/pubmed/15998454
http://dx.doi.org/10.1186/gb-2005-6-7-115
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author Aloni, Ronny
Lancet, Doron
author_facet Aloni, Ronny
Lancet, Doron
author_sort Aloni, Ronny
collection PubMed
description Genomic segments that do not code for proteins yet show high conservation among vertebrates have recently been identified by various computational methodologies. We refer to them as ANCORs (ancestral non-coding conserved regions). The frequency of individual ANCORs within the genome, along with their (correlated) inter-species identity scores, helps in assessing the probability that they function in transcription regulation or RNA coding.
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spelling pubmed-11759772005-07-17 Conservation anchors in the vertebrate genome Aloni, Ronny Lancet, Doron Genome Biol Opinion Genomic segments that do not code for proteins yet show high conservation among vertebrates have recently been identified by various computational methodologies. We refer to them as ANCORs (ancestral non-coding conserved regions). The frequency of individual ANCORs within the genome, along with their (correlated) inter-species identity scores, helps in assessing the probability that they function in transcription regulation or RNA coding. BioMed Central 2005 2005-06-29 /pmc/articles/PMC1175977/ /pubmed/15998454 http://dx.doi.org/10.1186/gb-2005-6-7-115 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Opinion
Aloni, Ronny
Lancet, Doron
Conservation anchors in the vertebrate genome
title Conservation anchors in the vertebrate genome
title_full Conservation anchors in the vertebrate genome
title_fullStr Conservation anchors in the vertebrate genome
title_full_unstemmed Conservation anchors in the vertebrate genome
title_short Conservation anchors in the vertebrate genome
title_sort conservation anchors in the vertebrate genome
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175977/
https://www.ncbi.nlm.nih.gov/pubmed/15998454
http://dx.doi.org/10.1186/gb-2005-6-7-115
work_keys_str_mv AT alonironny conservationanchorsinthevertebrategenome
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