Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human

We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent a...

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Detalles Bibliográficos
Autores principales: Magness, Charles L, Fellin, P Campion, Thomas, Matthew J, Korth, Marcus J, Agy, Michael B, Proll, Sean C, Fitzgibbon, Matthew, Scherer, Christina A, Miner, Douglas G, Katze, Michael G, Iadonato, Shawn P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175991/
https://www.ncbi.nlm.nih.gov/pubmed/15998449
http://dx.doi.org/10.1186/gb-2005-6-7-r60
Descripción
Sumario:We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.

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