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Validation and refinement of gene-regulatory pathways on a network of physical interactions
As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternati...
Autores principales: | Yeang, Chen-Hsiang, Mak, H Craig, McCuine, Scott, Workman, Christopher, Jaakkola, Tommi, Ideker, Trey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175993/ https://www.ncbi.nlm.nih.gov/pubmed/15998451 http://dx.doi.org/10.1186/gb-2005-6-7-r62 |
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