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Validation and refinement of gene-regulatory pathways on a network of physical interactions

As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternati...

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Detalles Bibliográficos
Autores principales: Yeang, Chen-Hsiang, Mak, H Craig, McCuine, Scott, Workman, Christopher, Jaakkola, Tommi, Ideker, Trey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175993/
https://www.ncbi.nlm.nih.gov/pubmed/15998451
http://dx.doi.org/10.1186/gb-2005-6-7-r62

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