The GTPase switch in ribosomal translocation

Information from careful measurements of the affinity of ribosome-associated proteins for GTP and GDP, and from structural analyses, suggests that elongation factor-G must assume three different structures during protein synthesis and that the ribosome itself acts as a guanine-nucleotide exchange fa...

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Detalles Bibliográficos
Autor principal: Moore, Pete
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176000/
https://www.ncbi.nlm.nih.gov/pubmed/15985152
http://dx.doi.org/10.1186/jbiol28
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author Moore, Pete
author_facet Moore, Pete
author_sort Moore, Pete
collection PubMed
description Information from careful measurements of the affinity of ribosome-associated proteins for GTP and GDP, and from structural analyses, suggests that elongation factor-G must assume three different structures during protein synthesis and that the ribosome itself acts as a guanine-nucleotide exchange factor. Is it time to re-write the textbook description of translation?
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spelling pubmed-11760002005-07-17 The GTPase switch in ribosomal translocation Moore, Pete J Biol Research News Information from careful measurements of the affinity of ribosome-associated proteins for GTP and GDP, and from structural analyses, suggests that elongation factor-G must assume three different structures during protein synthesis and that the ribosome itself acts as a guanine-nucleotide exchange factor. Is it time to re-write the textbook description of translation? BioMed Central 2005 2005-06-27 /pmc/articles/PMC1176000/ /pubmed/15985152 http://dx.doi.org/10.1186/jbiol28 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Research News
Moore, Pete
The GTPase switch in ribosomal translocation
title The GTPase switch in ribosomal translocation
title_full The GTPase switch in ribosomal translocation
title_fullStr The GTPase switch in ribosomal translocation
title_full_unstemmed The GTPase switch in ribosomal translocation
title_short The GTPase switch in ribosomal translocation
title_sort gtpase switch in ribosomal translocation
topic Research News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176000/
https://www.ncbi.nlm.nih.gov/pubmed/15985152
http://dx.doi.org/10.1186/jbiol28
work_keys_str_mv AT moorepete thegtpaseswitchinribosomaltranslocation
AT moorepete gtpaseswitchinribosomaltranslocation

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