C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages

BACKGROUND: It has been reported that C-reactive protein (CRP) binds both leukocyte FcγRIIA (CD32) and the plasma membrane of apoptotic cells. Since FcγRIIA becomes functionally enabled during neutrophil apoptosis, we sought to determine whether CRP bound to apoptotic neutrophils via FcγRIIA. METHOD...

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Detalles Bibliográficos
Autores principales: Hart, Simon P, Alexander, Karen M, MacCall, Shonna M, Dransfield, Ian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177984/
https://www.ncbi.nlm.nih.gov/pubmed/15927062
http://dx.doi.org/10.1186/1476-9255-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177984/
https://www.ncbi.nlm.nih.gov/pubmed/15927062
http://dx.doi.org/10.1186/1476-9255-2-5

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