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Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland

BACKGROUND: The plant stanol ester margarine Benecol(® )is a functional food that has been shown to lower effectively serum total and LDL-cholesterol. The purpose of this post-marketing study is to characterize users of plant stanol ester margarine with and without cardiovascular disease. METHODS: A...

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Autores principales: Simojoki, Meri, Luoto, Riitta, Uutela, Antti, Rita, Hannu, Boice, John D, McLaughlin, Joseph K, Puska, Pekka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177987/
https://www.ncbi.nlm.nih.gov/pubmed/15929790
http://dx.doi.org/10.1186/1475-2891-4-20
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author Simojoki, Meri
Luoto, Riitta
Uutela, Antti
Rita, Hannu
Boice, John D
McLaughlin, Joseph K
Puska, Pekka
author_facet Simojoki, Meri
Luoto, Riitta
Uutela, Antti
Rita, Hannu
Boice, John D
McLaughlin, Joseph K
Puska, Pekka
author_sort Simojoki, Meri
collection PubMed
description BACKGROUND: The plant stanol ester margarine Benecol(® )is a functional food that has been shown to lower effectively serum total and LDL-cholesterol. The purpose of this post-marketing study is to characterize users of plant stanol ester margarine with and without cardiovascular disease. METHODS: A cohort of plant stanol ester margarine users was established based on a compilation of 15 surveys conducted by the National Public Health Institute in Finland between 1996–2000. There were 29 772 subjects aged 35–84 years in the cohort. The users of plant stanol ester margarine were identified by the type of bread spread used. RESULTS: The plant stanol ester margarine was used as bread spread by 1332 (4.5%) subjects. Almost half (46%) of the users reported a history of cardiovascular disease. Persons with cardiovascular disease were more likely to use plant stanol ester margarine (8%) than persons without cardiovascular disease (3%). Users with and without cardiovascular disease seemed to share similar characteristics. In particular, they were elderly people with otherwise healthy life-styles and diet. They were less likely smokers, more likely physically active and less likely obese than nonusers. The users reported being in good or average health in general and having used cholesterol-lowering drugs. CONCLUSION: Plant stanol ester margarine seems to be used by persons for whom it was designed and in a way it was meant: as part of efforts for cardiovascular disease risk reduction.
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spelling pubmed-11779872005-07-21 Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland Simojoki, Meri Luoto, Riitta Uutela, Antti Rita, Hannu Boice, John D McLaughlin, Joseph K Puska, Pekka Nutr J Research BACKGROUND: The plant stanol ester margarine Benecol(® )is a functional food that has been shown to lower effectively serum total and LDL-cholesterol. The purpose of this post-marketing study is to characterize users of plant stanol ester margarine with and without cardiovascular disease. METHODS: A cohort of plant stanol ester margarine users was established based on a compilation of 15 surveys conducted by the National Public Health Institute in Finland between 1996–2000. There were 29 772 subjects aged 35–84 years in the cohort. The users of plant stanol ester margarine were identified by the type of bread spread used. RESULTS: The plant stanol ester margarine was used as bread spread by 1332 (4.5%) subjects. Almost half (46%) of the users reported a history of cardiovascular disease. Persons with cardiovascular disease were more likely to use plant stanol ester margarine (8%) than persons without cardiovascular disease (3%). Users with and without cardiovascular disease seemed to share similar characteristics. In particular, they were elderly people with otherwise healthy life-styles and diet. They were less likely smokers, more likely physically active and less likely obese than nonusers. The users reported being in good or average health in general and having used cholesterol-lowering drugs. CONCLUSION: Plant stanol ester margarine seems to be used by persons for whom it was designed and in a way it was meant: as part of efforts for cardiovascular disease risk reduction. BioMed Central 2005-06-01 /pmc/articles/PMC1177987/ /pubmed/15929790 http://dx.doi.org/10.1186/1475-2891-4-20 Text en Copyright © 2005 Simojoki et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Simojoki, Meri
Luoto, Riitta
Uutela, Antti
Rita, Hannu
Boice, John D
McLaughlin, Joseph K
Puska, Pekka
Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title_full Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title_fullStr Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title_full_unstemmed Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title_short Use of plant stanol ester margarine among persons with and without cardiovascular disease: Early phases of the adoption of a functional food in Finland
title_sort use of plant stanol ester margarine among persons with and without cardiovascular disease: early phases of the adoption of a functional food in finland
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177987/
https://www.ncbi.nlm.nih.gov/pubmed/15929790
http://dx.doi.org/10.1186/1475-2891-4-20
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