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Antigen-sensitized CD4(+)CD62L(low )memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting

BACKGROUND: Airway hyperresponsiveness (AHR) is one of the most prominent features of asthma, however, precise mechanisms for its induction have not been fully elucidated. We previously reported that systemic antigen sensitization alone directly induces AHR before development of eosinophilic airway...

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Detalles Bibliográficos
Autores principales: Nakagome, Kazuyuki, Dohi, Makoto, Okunishi, Katsuhide, To, Yasuo, Sato, Atsushi, Komagata, Yoshinori, Nagatani, Katsuya, Tanaka, Ryoichi, Yamamoto, Kazuhiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180472/
https://www.ncbi.nlm.nih.gov/pubmed/15921525
http://dx.doi.org/10.1186/1465-9921-6-46