Cargando…
Antigen-sensitized CD4(+)CD62L(low )memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting
BACKGROUND: Airway hyperresponsiveness (AHR) is one of the most prominent features of asthma, however, precise mechanisms for its induction have not been fully elucidated. We previously reported that systemic antigen sensitization alone directly induces AHR before development of eosinophilic airway...
Autores principales: | Nakagome, Kazuyuki, Dohi, Makoto, Okunishi, Katsuhide, To, Yasuo, Sato, Atsushi, Komagata, Yoshinori, Nagatani, Katsuya, Tanaka, Ryoichi, Yamamoto, Kazuhiko |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180472/ https://www.ncbi.nlm.nih.gov/pubmed/15921525 http://dx.doi.org/10.1186/1465-9921-6-46 |
Ejemplares similares
-
Preferential Accumulation of Antigen-specific Effector CD4 T Cells at an Antigen Injection Site Involves CD62E-dependent Migration but Not Local Proliferation
por: Reinhardt, R. Lee, et al.
Publicado: (2003) -
Essential Contribution of CD4(+) T Cells to Antigen-Induced Nasal Hyperresponsiveness in Experimental Allergic Rhinitis
por: Nishimura, Tomoe, et al.
Publicado: (2016) -
Essential role of Notch signaling in effector memory CD8(+) T cell–mediated airway hyperresponsiveness and inflammation
por: Okamoto, Masakazu, et al.
Publicado: (2008) -
Expression of Concern: Essential Contribution of CD4(+) T Cells to Antigen-Induced Nasal Hyperresponsiveness in Experimental Allergic Rhinitis
Publicado: (2023) -
Reversal of airway hyperresponsiveness by induction of airway mucosal CD4(+)CD25(+) regulatory T cells
por: Strickland, Deborah H., et al.
Publicado: (2006)