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Chlamydophila pneumoniae induces expression of Toll-like Receptor 4 and release of TNF-α and MIP-2 via an NF-κB pathway in rat type II pneumocytes

BACKGROUND: The role of alveolar type II cells in the regulation of innate and adaptive immunity is unclear. Toll-like receptors (TLRs) have been implicated in host defense. The purpose of the present study was to investigate whether Chlamydophila pneumoniae (I) alters the expression of TLR2 and/orT...

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Detalles Bibliográficos
Autores principales: Wissel, Heide, Schulz, Christian, Koehne, Petra, Richter, Ekkehard, Maass, Matthias, Rüdiger, Mario
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180473/
https://www.ncbi.nlm.nih.gov/pubmed/15935092
http://dx.doi.org/10.1186/1465-9921-6-51