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Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells

BACKGROUND: Mammalian reoviruses naturally infect their hosts through the enteric and respiratory tracts. During enteric infections, proteolysis of the reovirus outer capsid protein σ3 is mediated by pancreatic serine proteases. In contrast, the proteases critical for reovirus replication in the lun...

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Detalles Bibliográficos
Autores principales: Golden, Joseph W, Schiff, Leslie A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180477/
https://www.ncbi.nlm.nih.gov/pubmed/15927073
http://dx.doi.org/10.1186/1743-422X-2-48

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