The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase

Three conserved aspartate residues in the largest subunit of multisubunit RNA polymerases (RNAPs) coordinate two Mg(2+) ions involved in the catalysis of phosphodiester bond synthesis. A structural model based on the stereochemistry of nucleotidyl transfer reaction as well as recent crystallographic...

Descripción completa

Detalles Bibliográficos
Autores principales: Sosunov, Vasily, Zorov, Savva, Sosunova, Ekaterina, Nikolaev, Anatoly, Zakeyeva, Irina, Bass, Irina, Goldfarb, Alex, Nikiforov, Vadim, Severinov, Konstantin, Mustaev, Arkady
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180743/
https://www.ncbi.nlm.nih.gov/pubmed/16049026
http://dx.doi.org/10.1093/nar/gki688

Ejemplares similares

Ejemplares similares