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Cooperative binding of DNA and CBFβ to the Runt domain of the CBFα studied via MD simulations
The Runt domain (RD) is the DNA-binding region of the Runx genes. A related protein, known as core binding factor β (CBFβ) also binds to the RD to enhance RD–DNA interaction by 6- to 10-fold. Here, we report results from molecular dynamics (MD) simulations of RD alone, as a dimer in complexes with D...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180745/ https://www.ncbi.nlm.nih.gov/pubmed/16049027 http://dx.doi.org/10.1093/nar/gki724 |