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Anti-proliferative effects, cell cycle G(2)/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines
BACKGROUND: Anticancer bisdioxopiperazines, including ICRF-154, razoxane (Raz, ICRF-159) and ICRF-193, are a family of anticancer agents developed in the UK, especially targeting metastases of neoplasms. Two other bisdioxopiperazine derivatives, probimane (Pro) and MST-16, were synthesized at the Sh...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180833/ https://www.ncbi.nlm.nih.gov/pubmed/15963241 http://dx.doi.org/10.1186/1471-2210-5-11 |