Cargando…

Determination of protein–DNA binding constants and specificities from statistical analyses of single molecules: MutS–DNA interactions

Atomic force microscopy (AFM) is a powerful technique for examining the conformations of protein–DNA complexes and determining the stoichiometries and affinities of protein–protein complexes. We extend the capabilities of AFM to the determination of protein–DNA binding constants and specificities. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yong, Sass, Lauryn E., Du, Chunwei, Hsieh, Peggy, Erie, Dorothy A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182163/
https://www.ncbi.nlm.nih.gov/pubmed/16061937
http://dx.doi.org/10.1093/nar/gki708