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Determination of protein–DNA binding constants and specificities from statistical analyses of single molecules: MutS–DNA interactions
Atomic force microscopy (AFM) is a powerful technique for examining the conformations of protein–DNA complexes and determining the stoichiometries and affinities of protein–protein complexes. We extend the capabilities of AFM to the determination of protein–DNA binding constants and specificities. T...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182163/ https://www.ncbi.nlm.nih.gov/pubmed/16061937 http://dx.doi.org/10.1093/nar/gki708 |