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Base excision repair intermediates are mutagenic in mammalian cells

Base excision repair (BER) is the main pathway for repair of DNA damage in mammalian cells. This pathway leads to the formation of DNA repair intermediates which, if still unsolved, cause cell lethality and mutagenesis. To characterize mutations induced by BER intermediates in mammalian cells, an SV...

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Detalles Bibliográficos
Autores principales: Simonelli, Valeria, Narciso, Laura, Dogliotti, Eugenia, Fortini, Paola
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182698/
https://www.ncbi.nlm.nih.gov/pubmed/16077026
http://dx.doi.org/10.1093/nar/gki749