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Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

Apurinic apyrimidinic endonuclease redox effector factor-1 (APE1/Ref-1) is involved both in the base excision repair (BER) of DNA lesions and in the eukaryotic transcriptional regulation. APE1/Ref-1 is regulated at both the transcriptional and post-translational levels, through control of subcellula...

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Detalles Bibliográficos
Autores principales:	Pines, Alex, Perrone, Lorena, Bivi, Nicoletta, Romanello, Milena, Damante, Giuseppe, Gulisano, Massimo, Kelley, Mark R., Quadrifoglio, Franco, Tell, Gianluca
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182699/ https://www.ncbi.nlm.nih.gov/pubmed/16077024 http://dx.doi.org/10.1093/nar/gki751

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