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FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis
BACKGROUND: Analyses of Fgf10 and Fgfr2b mutant mice, as well as human studies, suggest that FGF10/FGFR2b signaling may play an essential, nonredundant role during embryonic SMG development. To address this question, we have analyzed the SMG phenotype in Fgf10 and Fgfr2b heterozygous and null mutant...
Autores principales: | Jaskoll, Tina, Abichaker, George, Witcher, Daniel, Sala, Frederic G, Bellusci, Saverio, Hajihosseini, Mohammad K, Melnick, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184065/ https://www.ncbi.nlm.nih.gov/pubmed/15972105 http://dx.doi.org/10.1186/1471-213X-5-11 |
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