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A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion
BACKGROUND: Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the proliferation, migration and contraction of retinal pigmented epithelial cells (RPE), and these cellular responses are influenced by the expression...
Autores principales: | Hoffmann, Stephan, He, Shikun, Jin, Manlin, Ehren, Marianne, Wiedemann, Peter, Ryan, Stephen J, Hinton, David R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184086/ https://www.ncbi.nlm.nih.gov/pubmed/15987521 http://dx.doi.org/10.1186/1471-2415-5-16 |
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