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Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents

BACKGROUND: Insulin resistance is the best predictor for the development of type 2 diabetes. Recent studies have shown that young, lean, insulin-resistant (IR) offspring of parents with type 2 diabetes have reduced basal rates of muscle mitochondrial phosphorylation activity associated with increase...

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Detalles Bibliográficos
Autores principales:	Petersen, Kitt F, Dufour, Sylvie, Shulman, Gerald I
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184227/ https://www.ncbi.nlm.nih.gov/pubmed/16089501 http://dx.doi.org/10.1371/journal.pmed.0020233

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