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Functional Identification of Catalytic Metal Ion Binding Sites within RNA

The viability of living systems depends inextricably on enzymes that catalyze phosphoryl transfer reactions. For many enzymes in this class, including several ribozymes, divalent metal ions serve as obligate cofactors. Understanding how metal ions mediate catalysis requires elucidation of metal ion...

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Detalles Bibliográficos
Autores principales:	Hougland, James L, Kravchuk, Alexander V, Herschlag, Daniel, Piccirilli, Joseph A
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184590/ https://www.ncbi.nlm.nih.gov/pubmed/16092891 http://dx.doi.org/10.1371/journal.pbio.0030277

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