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Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions. Ex vivo expansion of pure populations of tiss...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184591/ https://www.ncbi.nlm.nih.gov/pubmed/16086633 http://dx.doi.org/10.1371/journal.pbio.0030283 |