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Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell

Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions. Ex vivo expansion of pure populations of tiss...

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Detalles Bibliográficos
Autores principales:	Conti, Luciano, Pollard, Steven M, Gorba, Thorsten, Reitano, Erika, Toselli, Mauro, Biella, Gerardo, Sun, Yirui, Sanzone, Sveva, Ying, Qi-Long, Cattaneo, Elena, Smith, Austin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184591/ https://www.ncbi.nlm.nih.gov/pubmed/16086633 http://dx.doi.org/10.1371/journal.pbio.0030283

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