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Genetic loci for ventricular dilatation in the LEW/Jms rat with fetal-onset hydrocephalus are influenced by gender and genetic background

BACKGROUND: The LEW/Jms rat strain has inherited hydrocephalus, with more males affected than females and an overall expression rate of 28%. This study aimed to determine chromosomal positions for genetic loci causing the hydrocephalus. METHODS: An F(1 )backcross was made to the parental LEW/Jms str...

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Detalles Bibliográficos
Autores principales: Jones, Hazel C, Totten, Crystal F, Mayorga, David A, Yue, Mei, Carter, Barbara J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185556/
https://www.ncbi.nlm.nih.gov/pubmed/15953386
http://dx.doi.org/10.1186/1743-8454-2-2