Synergistic defect in 60S ribosomal subunit assembly caused by a mutation of Rrs1p, a ribosomal protein L11-binding protein, and 3′-extension of 5S rRNA in Saccharomyces cerevisiae

Rrs1p, a ribosomal protein L11-binding protein, has an essential role in biogenesis of 60S ribosomal subunits. We obtained conditionally synthetic lethal allele with the rrs1-5 mutation and determined that the mutation is in REX1, which encodes an exonuclease. The highly conserved leucine at 305 was...

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Detalles Bibliográficos
Autores principales: Nariai, Masanobu, Tanaka, Tomohisa, Okada, Takafumi, Shirai, Chiharu, Horigome, Chihiro, Mizuta, Keiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185577/
https://www.ncbi.nlm.nih.gov/pubmed/16100378
http://dx.doi.org/10.1093/nar/gki772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185577/
https://www.ncbi.nlm.nih.gov/pubmed/16100378
http://dx.doi.org/10.1093/nar/gki772

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