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DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE
POU domain proteins contain a bipartite DNA-binding element that can confer allosteric control of coactivator recruitment. Dimerization of Oct-1 and Oct-2 on palindromic response elements results in the conformational dependent inclusion or exclusion of the transcriptional coactivator OBF-1. In this...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187819/ https://www.ncbi.nlm.nih.gov/pubmed/16103132 http://dx.doi.org/10.1093/nar/gki744 |