Cargando…

DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE

POU domain proteins contain a bipartite DNA-binding element that can confer allosteric control of coactivator recruitment. Dimerization of Oct-1 and Oct-2 on palindromic response elements results in the conformational dependent inclusion or exclusion of the transcriptional coactivator OBF-1. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Malin, Stephen, Linderson, Ylva, Almqvist, Jenny, Ernberg, Ingemar, Tallone, Tiziano, Pettersson, Sven
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187819/
https://www.ncbi.nlm.nih.gov/pubmed/16103132
http://dx.doi.org/10.1093/nar/gki744