Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance

Neurodegeneration can occur as a result of endogenous oxidative stress. Primary cerebellar granule cells were used in this study to determine if mitochondrial DNA (mtDNA) repair deficiencies correlate with oxidative stress-induced apoptosis in neuronal cells. Granule cells exhibited a significantly...

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Detalles Bibliográficos
Autores principales: Harrison, Jason F., Hollensworth, Scott B., Spitz, Douglas R., Copeland, William C., Wilson, Glenn L., LeDoux, Susan P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187820/
https://www.ncbi.nlm.nih.gov/pubmed/16107556
http://dx.doi.org/10.1093/nar/gki759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187820/
https://www.ncbi.nlm.nih.gov/pubmed/16107556
http://dx.doi.org/10.1093/nar/gki759

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