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Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52
When exogenous DNA is stably introduced in mammalian cells, it is typically integrated in random positions, and only a minor fraction enters a pathway of homologous recombination (HR). The complex Rad51/Rad52 is a major player in the management of exogenous DNA in eukaryotic organisms and plays a cr...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187822/ https://www.ncbi.nlm.nih.gov/pubmed/16106043 http://dx.doi.org/10.1093/nar/gki778 |