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Methylation-Specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences

Copy number changes and CpG methylation of various genes are hallmarks of tumor development but are not yet widely used in diagnostic settings. The recently developed multiplex ligation-dependent probe amplification (MLPA) method has increased the possibilities for multiplex detection of gene copy n...

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Detalles Bibliográficos
Autores principales:	Nygren, Anders O. H., Ameziane, Najim, Duarte, Helena M. B., Vijzelaar, Raymon N. C. P., Waisfisz, Quinten, Hess, Corine J., Schouten, Jan P., Errami, Abdellatif
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187824/ https://www.ncbi.nlm.nih.gov/pubmed/16106041 http://dx.doi.org/10.1093/nar/gni127

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