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Delayed polarization of mononuclear phagocyte transcriptional program by type I interferon isoforms

BACKGROUND: Interferon (IFN)-α is considered a key modulator of immunopathological processes through a signature-specific activation of mononuclear phagocytes (MPs). This study utilized global transcript analysis to characterize the effects of the entire type I IFN family in comparison to a broad pa...

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Detalles Bibliográficos
Autores principales: Stroncek, David F, Basil, Christopher, Nagorsen, Dirk, Deola, Sara, Aricó, Eleonora, Smith, Kina, Wang, Ena, Marincola, Francesco M, Panelli, Monica C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187927/
https://www.ncbi.nlm.nih.gov/pubmed/15953390
http://dx.doi.org/10.1186/1479-5876-3-24

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