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Functional Coverage of the Human Genome by Existing Structures, Structural Genomics Targets, and Homology Models

The bias in protein structure and function space resulting from experimental limitations and targeting of particular functional classes of proteins by structural biologists has long been recognized, but never continuously quantified. Using the Enzyme Commission and the Gene Ontology classifications...

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Detalles Bibliográficos
Autores principales: Xie, Lei, Bourne, Philip E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188274/
https://www.ncbi.nlm.nih.gov/pubmed/16118666
http://dx.doi.org/10.1371/journal.pcbi.0010031