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HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor
BACKGROUND: Hypoxia-inducible factor 1 (HIF-1) is a transcription factor, which plays a central role in biologic processes under hypoxic conditions, especially concerning tumour angiogenesis. HIF-1α is the relevant, oxygen-dependent subunit and its overexpression has been associated with a poor prog...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190162/ https://www.ncbi.nlm.nih.gov/pubmed/16035955 http://dx.doi.org/10.1186/1471-2407-5-84 |