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Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells

BACKGROUND: Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis. Tissue factor (TF) is critical in thrombosis. This study investigated the effect of...

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Detalles Bibliográficos
Autores principales:	Zhu, Shengsi, Viswambharan, Hema, Gajanayake, Thusitha, Ming, Xiu-Fen, Yang, Zhihong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190166/ https://www.ncbi.nlm.nih.gov/pubmed/16018822 http://dx.doi.org/10.1186/1471-2261-5-22

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