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Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid
BACKGROUND: Interleukin 1 (IL-1) is a key mediator of immune responses in health and disease. Although classically the function of IL-1 has been studied in the systemic immune system, research in the past decade has revealed analogous roles in the CNS where the cytokine can contribute to the neuroin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190207/ https://www.ncbi.nlm.nih.gov/pubmed/15967035 http://dx.doi.org/10.1186/1742-2094-2-15 |