Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor

BACKGROUND: Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications. The endothelial cells are the first cells targeted by hyperglycemia. The mechanism of endothelial injury by high glucose is still poorly understood. Heparanase production, induced by...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Juying, Mandal, Anil K, Hiebert, Linda M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1192813/
https://www.ncbi.nlm.nih.gov/pubmed/16086844
http://dx.doi.org/10.1186/1475-2840-4-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1192813/
https://www.ncbi.nlm.nih.gov/pubmed/16086844
http://dx.doi.org/10.1186/1475-2840-4-12

Ejemplares similares