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What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ?
At times of crisis when epidemics rage and begin to take their toll on affected populations, as we have been witnessing with African trypanosomiasis in subSahara, the dichotomy of basic versus applied research deepens. While undoubtedly the treatment of thousands of infected people is the top priori...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC119325/ https://www.ncbi.nlm.nih.gov/pubmed/12234385 http://dx.doi.org/10.1186/1475-9292-1-4 |
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author | Aksoy, Serap Hao, Zhengrong Strickler, Patricia M |
author_facet | Aksoy, Serap Hao, Zhengrong Strickler, Patricia M |
author_sort | Aksoy, Serap |
collection | PubMed |
description | At times of crisis when epidemics rage and begin to take their toll on affected populations, as we have been witnessing with African trypanosomiasis in subSahara, the dichotomy of basic versus applied research deepens. While undoubtedly the treatment of thousands of infected people is the top priority, without continued research and development on the biology of disease agents and on ecological and evolutionary forces impacting these epidemics, little progress can be gained in the long run for the eventual control of these diseases. Here, we argue the need for additional research in one under-investigated area, that is the biology of the tsetse vector. Lacking are studies aimed to understand the genetic and cellular basis of tsetse interactions with trypanosomes as well as the genetic and biochemical basis of its ability to transmit these parasites. We discuss how this knowledge has the potential to contribute to the development of new vector control strategies as well as to improve the efficacy and affordability of the existing control approaches. |
format | Text |
id | pubmed-119325 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-1193252002-09-10 What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? Aksoy, Serap Hao, Zhengrong Strickler, Patricia M Kinetoplastid Biol Dis Review At times of crisis when epidemics rage and begin to take their toll on affected populations, as we have been witnessing with African trypanosomiasis in subSahara, the dichotomy of basic versus applied research deepens. While undoubtedly the treatment of thousands of infected people is the top priority, without continued research and development on the biology of disease agents and on ecological and evolutionary forces impacting these epidemics, little progress can be gained in the long run for the eventual control of these diseases. Here, we argue the need for additional research in one under-investigated area, that is the biology of the tsetse vector. Lacking are studies aimed to understand the genetic and cellular basis of tsetse interactions with trypanosomes as well as the genetic and biochemical basis of its ability to transmit these parasites. We discuss how this knowledge has the potential to contribute to the development of new vector control strategies as well as to improve the efficacy and affordability of the existing control approaches. BioMed Central 2002-06-06 /pmc/articles/PMC119325/ /pubmed/12234385 http://dx.doi.org/10.1186/1475-9292-1-4 Text en Copyright © 2002 Aksoy et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. |
spellingShingle | Review Aksoy, Serap Hao, Zhengrong Strickler, Patricia M What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title | What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title_full | What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title_fullStr | What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title_full_unstemmed | What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title_short | What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
title_sort | what can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC119325/ https://www.ncbi.nlm.nih.gov/pubmed/12234385 http://dx.doi.org/10.1186/1475-9292-1-4 |
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