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Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung. METHODS AND FINDINGS: Using oligonucleotide arrays, we identified osteopontin as one of the genes that significantl...

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Detalles Bibliográficos
Autores principales:	Pardo, Annie, Gibson, Kevin, Cisneros, José, Richards, Thomas J, Yang, Yinke, Becerril, Carina, Yousem, Samueal, Herrera, Iliana, Ruiz, Victor, Selman, Moisés, Kaminski, Naftali
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198037/ https://www.ncbi.nlm.nih.gov/pubmed/16128620 http://dx.doi.org/10.1371/journal.pmed.0020251

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