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Modelling of oedemous limbs and venous ulcers using partial differential equations

BACKGROUND: Oedema, commonly known as tissue swelling, occurs mainly on the leg and the arm. The condition may be associated with a range of causes such as venous diseases, trauma, infection, joint disease and orthopaedic surgery. Oedema is caused by both lymphatic and chronic venous insufficiency,...

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Detalles Bibliográficos
Autores principales: Ugail, Hassan, Wilson, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198260/
https://www.ncbi.nlm.nih.gov/pubmed/16078992
http://dx.doi.org/10.1186/1742-4682-2-28
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author Ugail, Hassan
Wilson, Michael J
author_facet Ugail, Hassan
Wilson, Michael J
author_sort Ugail, Hassan
collection PubMed
description BACKGROUND: Oedema, commonly known as tissue swelling, occurs mainly on the leg and the arm. The condition may be associated with a range of causes such as venous diseases, trauma, infection, joint disease and orthopaedic surgery. Oedema is caused by both lymphatic and chronic venous insufficiency, which leads to pooling of blood and fluid in the extremities. This results in swelling, mild redness and scaling of the skin, all of which can culminate in ulceration. METHODS: We present a method to model a wide variety of geometries of limbs affected by oedema and venous ulcers. The shape modelling is based on the PDE method where a set of boundary curves are extracted from 3D scan data and are utilised as boundary conditions to solve a PDE, which provides the geometry of an affected limb. For this work we utilise a mixture of fourth order and sixth order PDEs, the solutions of which enable us to obtain a good representative shape of the limb and associated ulcers in question. RESULTS: A series of examples are discussed demonstrating the capability of the method to produce good representative shapes of limbs by utilising a series of curves extracted from the scan data. In particular we show how the method could be used to model the shape of an arm and a leg with an associated ulcer. CONCLUSION: We show how PDE based shape modelling techniques can be utilised to generate a variety of limb shapes and associated ulcers by means of a series of curves extracted from scan data. We also discuss how the method could be used to manipulate a generic shape of a limb and an associated wound so that the model could be fine-tuned for a particular patient.
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spelling pubmed-11982602005-09-03 Modelling of oedemous limbs and venous ulcers using partial differential equations Ugail, Hassan Wilson, Michael J Theor Biol Med Model Research BACKGROUND: Oedema, commonly known as tissue swelling, occurs mainly on the leg and the arm. The condition may be associated with a range of causes such as venous diseases, trauma, infection, joint disease and orthopaedic surgery. Oedema is caused by both lymphatic and chronic venous insufficiency, which leads to pooling of blood and fluid in the extremities. This results in swelling, mild redness and scaling of the skin, all of which can culminate in ulceration. METHODS: We present a method to model a wide variety of geometries of limbs affected by oedema and venous ulcers. The shape modelling is based on the PDE method where a set of boundary curves are extracted from 3D scan data and are utilised as boundary conditions to solve a PDE, which provides the geometry of an affected limb. For this work we utilise a mixture of fourth order and sixth order PDEs, the solutions of which enable us to obtain a good representative shape of the limb and associated ulcers in question. RESULTS: A series of examples are discussed demonstrating the capability of the method to produce good representative shapes of limbs by utilising a series of curves extracted from the scan data. In particular we show how the method could be used to model the shape of an arm and a leg with an associated ulcer. CONCLUSION: We show how PDE based shape modelling techniques can be utilised to generate a variety of limb shapes and associated ulcers by means of a series of curves extracted from scan data. We also discuss how the method could be used to manipulate a generic shape of a limb and an associated wound so that the model could be fine-tuned for a particular patient. BioMed Central 2005-08-03 /pmc/articles/PMC1198260/ /pubmed/16078992 http://dx.doi.org/10.1186/1742-4682-2-28 Text en Copyright © 2005 Ugail and Wilson; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ugail, Hassan
Wilson, Michael J
Modelling of oedemous limbs and venous ulcers using partial differential equations
title Modelling of oedemous limbs and venous ulcers using partial differential equations
title_full Modelling of oedemous limbs and venous ulcers using partial differential equations
title_fullStr Modelling of oedemous limbs and venous ulcers using partial differential equations
title_full_unstemmed Modelling of oedemous limbs and venous ulcers using partial differential equations
title_short Modelling of oedemous limbs and venous ulcers using partial differential equations
title_sort modelling of oedemous limbs and venous ulcers using partial differential equations
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198260/
https://www.ncbi.nlm.nih.gov/pubmed/16078992
http://dx.doi.org/10.1186/1742-4682-2-28
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