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Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity
Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly. To confirm this hypothesis and to enable a biochemical exa...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198262/ https://www.ncbi.nlm.nih.gov/pubmed/16105175 http://dx.doi.org/10.1186/1743-422X-2-63 |