Cargando…

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL), whereas HTLV type 2 (HTLV-2), is not associated with ATL or any other leukemia. HTLV-1 encodes the transforming gene tax1, whose expression in an interleukin (IL)-2-dependent T-cell line (C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsubata, Chikako, Higuchi, Masaya, Takahashi, Masahiko, Oie, Masayasu, Tanaka, Yuetsu, Gejyo, Fumitake, Fujii, Masahiro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199618/ https://www.ncbi.nlm.nih.gov/pubmed/16042787 http://dx.doi.org/10.1186/1742-4690-2-46

Ejemplares similares

Human T-cell leukemia virus type 2 Tax protein induces interleukin 2-independent growth in a T-cell line
por: Kondo, Rie, et al.
Publicado: (2006)

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2
por: Shoji, Toshiyuki, et al.
Publicado: (2009)

Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein
por: Ishioka, Kojiro, et al.
Publicado: (2006)

Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax
por: Higuchi, Masaya, et al.
Publicado: (2014)

Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells
por: Takachi, Takayuki, et al.
Publicado: (2015)

Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax
por: Mizuguchi, Mariko, et al.
Publicado: (2016)

An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
por: Belyaeva, Tamara A., et al.
Publicado: (2014)

PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice
por: Pérès, Eléonore, et al.
Publicado: (2018)

Distinct activities of HTLV-1 Tax1 from HTLV-2 Tax2 play key roles in pathogenesis
por: Fujii, Masahiro, et al.
Publicado: (2011)

Stress granules inhibit apoptosis by reducing ROS production, but this phenomenon is nullified by HTLV-1 Tax
por: Takahashi, Masahiko, et al.
Publicado: (2014)

Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein
por: Marsh, Elizabeth K., et al.
Publicado: (2017)

Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis
por: Higuchi, Masaya, et al.
Publicado: (2009)

HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation
por: Higuchi, Masaya, et al.
Publicado: (2011)

Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-κB activation
por: Higuchi, Masaya, et al.
Publicado: (2005)

The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
por: Cortés-Malagón, Enoc Mariano, et al.
Publicado: (2017)

Isolation and Characterization of Novel Human Parechovirus from Clinical Samples
por: Watanabe, Kanako, et al.
Publicado: (2007)

Inhibition of Tax transformation activity using a small molecule targeting Tax/PDZ domain interactions
por: Blibek, Karim, et al.
Publicado: (2014)

HTLV-1 Tax-activated NF-κB is involved in both cell growth and death
por: Mizuguchi, Mariko, et al.
Publicado: (2014)

Akt activation by human T-cell leukemia virus tax oncoprotein
por: Cherian, Mathew, et al.
Publicado: (2015)

A specificity map for HTLV-1 Tax/PDZ interactions
por: Blibek, Karim, et al.
Publicado: (2011)

An interaction map for HTLV-1 Tax and PDZ-containing proteins
por: Blibek, Karim, et al.
Publicado: (2014)

Move or Die: the Fate of the Tax Oncoprotein of HTLV-1
por: Lodewick, Julie, et al.
Publicado: (2011)

Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma
por: Yang, Liqun, et al.
Publicado: (2017)

EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses
por: Naito, Tadasuke, et al.
Publicado: (2019)

Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax
por: Wu, Xuefeng, et al.
Publicado: (2011)

Differential transforming activity of the retroviral Tax oncoproteins in human T lymphocytes
por: Ren, Tong, et al.
Publicado: (2013)

Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses
por: Heym, Stefanie, et al.
Publicado: (2022)

Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis
por: Kaneko, Yoshikatsu, et al.
Publicado: (2000)

Biochemical analysis of the diverse functions of the HTLV-1-encoded oncoprotein Tax
por: Nyborg, Jennifer K, et al.
Publicado: (2014)

Structural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ Domain
por: Mischo, André, et al.
Publicado: (2013)

Human T-cell leukemia virus type-I Tax induces the expression of CD83 on T cells
por: Tanaka, Yuetsu, et al.
Publicado: (2015)

Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif
por: Nagashima, Shunta, et al.
Publicado: (2016)

Suppression of type I interferon production by human T-cell leukemia virus type 1 oncoprotein Tax
por: Jin, Dong-Yan, et al.
Publicado: (2014)

Antagonistic effects of HTLV-1 Tax oncoprotein on BRCA1 expression and function
por: Huleihel, Mahmoud, et al.
Publicado: (2014)

PDZ Domains and Viral Infection: Versatile Potentials of HPV-PDZ Interactions in relation to Malignancy
por: Nagasaka, Kazunori, et al.
Publicado: (2013)

Post-translational modifications of the Tax oncoprotein of human T-cell leukemia virus control cytoplasmic and nuclear steps in Tax-mediated activation of the NF-κB pathway
por: Bex, Françoise, et al.
Publicado: (2009)

Ubiquitination-dependent, proteasomal degradation of the retroviral oncoprotein Tax by niclosamide, an anti-helminthic molecule
por: Xiang, Di, et al.
Publicado: (2014)

The HTLV-1 oncoprotein Tax is modified by the ubiquitin related modifier 1 (Urm1)
por: Hleihel, Rita, et al.
Publicado: (2018)

Zasp: A New Z-Band Alternatively Spliced PDZ-Motif Protein
por: Faulkner, Georgine, et al.
Publicado: (1999)

Prediction and Experimental Characterization of nsSNPs Altering Human PDZ-Binding Motifs
por: Gfeller, David, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k6hqfmk7gbhgn9r0srjntuapav