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Efficient trapping of HIV-1 envelope protein by hetero-oligomerization with an N-helix chimera

BACKGROUND: The N-heptad repeat region of the HIV-1 Transmembrane Envelope protein is a trimerization domain that forms part of a "six helix bundle" crucial to Envelope-mediated membrane fusion. N-heptad repeat peptides have been used as extracellular reagents to inhibit virus fusion. RESU...

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Detalles Bibliográficos
Autores principales:	Ou, Wu, Silver, Jonathan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199619/ https://www.ncbi.nlm.nih.gov/pubmed/16092970 http://dx.doi.org/10.1186/1742-4690-2-51

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