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Evidence that public database records for many cancer-associated genes reflect a splice form found in tumors and lack normal splice forms

Alternative splicing is widespread in the human genome, and it appears that many genes display different splice forms in cancerous tissue than in normal human tissues. However, since cDNAs for many cancer-associated genes were originally cloned from tumor samples, it is important to ask whether this...

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Detalles Bibliográficos
Autores principales: Roy, Meenakshi, Xu, Qiang, Lee, Christopher
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201329/
https://www.ncbi.nlm.nih.gov/pubmed/16147986
http://dx.doi.org/10.1093/nar/gki792