Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes

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Evidence from inbred strains of mice indicates that a quarter or more of the mammalian genome consists of chromosome regions containing clusters of functionally related genes. The intense selection pressures during inbreeding favor the coinheritance of optimal sets of alleles among these genetically...

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Detalles Bibliográficos
Autores principales: Petkov, Petko M, Graber, Joel H, Churchill, Gary A, DiPetrillo, Keith, King, Benjamin L, Paigen, Kenneth
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201368/
https://www.ncbi.nlm.nih.gov/pubmed/16163395
http://dx.doi.org/10.1371/journal.pgen.0010033

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