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Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes
Evidence from inbred strains of mice indicates that a quarter or more of the mammalian genome consists of chromosome regions containing clusters of functionally related genes. The intense selection pressures during inbreeding favor the coinheritance of optimal sets of alleles among these genetically...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201368/ https://www.ncbi.nlm.nih.gov/pubmed/16163395 http://dx.doi.org/10.1371/journal.pgen.0010033 |